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Phytophthora pathogenicity genes and Phytophthora identification

Adrienne Hardham, RSBS Plant Cell Biology Group

Synopsis

We are interested in identifying Phytophthora genes that function in the infection of host plants in order to contribute to our basic understanding of this process. These genes may also serve as targets for the development of novel control strategies. Genes of potential interest have been cloned. The image shown is of a tree killed by the P. cinnamomi, the "Dieback Fungus".

We have generated monoclonal antibodies specific for P. cinnamomi and P. nicotianae, and have developed a reliable dipstick assay for the rapid identification of these Phytophthora species. The dipstick assay is protected by patents in Australia and the USA (Hardham '93).

Hardham, A.R. and Cahill.D.M. (1993) Detection of motile organisms in a sample. Australian patent No. 48117/93 granted 1 May 1997. US Patent No. 5817472 granted 6 October 1998. European patent under examination.

Value

Diagnosis and control of Phytophthora would both be of major benefit to Australia. Phytophthora diseases cause widespread economic losses in important crops and major environmental problems in native ecosystems. Economic losses have been estimated to exceed $200m per annum. P. cinnamomi is a problem throughout the world.

Contacts

hardham@rsbs.anu.edu.au

BioTech RSBS