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Medical Diagnostic Technologies

Ted Maddess, Andrew James, RSBS Visual Sciences Group

Synopsis


Glaucoma testing: Based on the patented use of the frequency doubling illusion for diagnosisof glaucoma. This property is licensed to Welch Allyn Pty. USA, a large medical instrument company. Welch Allyn in turn have sold the marketing rights to the market leader in this area, Carl Zeiss Meditec . Glaucoma is the second commonest cause of blindness world wide affecting about 2% of the population over 50 years. The new test is quick, easy to use and highly accurate, having very low test retest variability in comparison with other perimeters.  The test has also proven to be useful in the diagnosis of other eye diseases.

A second-generation glaucoma test has been patented with Dr. Andrew James. This test is based on measuring electrical potentials from the scalp in response to visual stimuli related to those in the above device. The new device tests all parts of the visual field at the same time. Two patent and a PCT patent application have been filed.

A new project is a greatly improved evoked potential device for characterizing nerve damage be diseases like Multiple Sclerosis is under development. It could be marketed with the same hardware as the newer glaucoma tests. The objective is to match the diagnostic power of MRI and make the test accessible to physicians caring MS patients to permit more effective disease management.

Patents and Applications

James, A.C. & Maddess, T. (2000). Method and apparatus for assessing neural function by sparse stimuli. Australia, PCT/AU01/00343, WO 01/72211. National phase: Australia, Canada, Japan, Europe, USA.

Maddess, T. & James, A. (1998). Simultaneous binocular assessment of multiple optic nerve and cortical regions in diseases affecting nerve conduction. USA, Patent, No. 6,315,414; Australia, Patent, No. 732,471.

James, A.C. & Maddess, T. (1996). Glaucoma testing using non-linear systems identification techniques. USA, Patent, No. 5,539,482. Australia, Patent, No. 667,702.

Maddess, T.L. (1995). Early detection of glaucoma. USA, Patent, No. 5912723. Australia, Patent, No. 701075. European Patent App 95917232.1.

Maddess, T. (1994). Glaucoma testing from observations of optokinetic nystagmus. USA, Patent, No. 5,295,495. Australia, Patent, No. 645420.

Maddess, T. (1991). Method and apparatus for use in diagnosis of glaucoma. USA, Patent, No. 5,065,767. Australia, Patent, No. 611,585.

Contacts

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ted.maddess@anu.edu.au