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Plant cell cycle genes

Peter John, RSBS Plant Cell Biology Group

Synopsis

My research group filed a patent on the application of plant cell cycle genes in plant engineering with a view to improve plant growth and development as early as 1990. The patent application will provide broad coverage on the use of several key classes of cell cycle genes the use of which has been shown to affect plant growth, plant transformation, tolerance to stress, and development. The patent has been granted in Australia. A first set of claims was granted in the USA, the patent is under examination in other territories (Europe, Japan, Canada). On the basis of this patent application I entered into a research collaboration with Pioneer Hi-Bred to improve transformation in maize.

From 1998 until 2006, my group entered into a broad alliance with CropDesign NV, a new agricultural biotechnology company based in Belgium. CropDesign is now the holder of this patent application and supports further research in my laboratory, which in the meantime has led to the filing of two further patent applications on the use of cell cycle genes in plants. In addition, through its in-house research and a network of alliances with other leading cell cycle research teams CropDesign and its academic allies have built and continue to expand on a very strong IP platform relating to applications of cell cycle based technology in crops.

Among the patented applications of cell cycle technology are several areas that are of crucial importance to grain crops, e.g. tolerance to stress and disease, control of grain size and grain yield.

By collaboration with my group at ANU and with CropDesign, there is an opportunity to support further strategic work on the control of the cell cycle and the development of genetic strategies to improve crop plants. The company has indicated it is prepared to discuss appropriate arrangements with regard to intellectual property, which would secure access to state of the art technology for Australian agriculture.

Value

The initial ANU patent application providing broad coverage on the use of cell cycle genes in plants is extremely valuable in view of the broad range of application including increased yield, increased stress tolerance, disease resistance, quality traits which it covers. In addition other patent applications which are part of the CropDesign platform cover specific genes and /or specific uses.

The value of traits such as increased yield should be calculated as a percent of the value of the crop itself and new technology protection mechanisms allow us to capture a relevant part of the value added. This indicates that the value of the technology goes beyond the framework of the tradition seed business (a 15 Billion US$ market globally) and allows value creation and recovery in the much larger market for agricultural end-products. Access to this state of the art technology for Australian agriculture is essential in order to maintain its competitive position in the world market.

Contacts

john@rsbs.anu.edu.au

BioTech RSBS

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